Investigator Initiated Research at CVIT
CVIT is based in Kansas City, Missouri, and occupies independently-
leased facilities adjacent to Saint Luke's Cardiovascular Consultants.
All scientific and office computing facilities are networked through a
local area network internally and connected to all the imaging modality
computers and databases facilities at Saint Luke's Cardiovascular
Consultants. CVIT employs three internationally recognized full-time
PhD physicist/scientists in medical imaging, an internationally
recognized M.D. medical director, and a support staff of clinical research
associates, software programmers, technologists, administrative, grant
and technical writing staff. All employees are located at this facility with
full access to all Saint Luke's Cardiovascular Consultants equipment
and clinical operations per a research and technical service contract
with Saint Luke's.
The nuclear cardiology department operates its imaging services over a
wide-area network integrating 11 laboratories in office and hospital
environments with 11 SPECT cameras networked to a central laboratory
for data processing, clinical interpretation, reporting, databasing of
image, clinical and demographic data. A nuclear cardiology database,
established in 1987 contains over 120,000 patient entries with over 700
variables recorded per patient. This database is integrated with similar
databases for coronary catheterization, echocardiography and clinical
outcomes as a resource for clinical investigation. The center for
Cardiovascular and Radiological Imaging established in 2001 within
Saint Luke's Cardiovascular Consultants is a 2,200 sq. foot facility with
PET, PET/CT and CT laboratories for cardiac application.
The main facility for nuclear cardiology has 3 SPECT systems: 2 ADAC
dual 90 detector CardioTM systems, both with scanning Gd-153 line
sources for attenuation correction and a dual 90o detector Siemens e.
camTM with a fixed array of Gd-153 sources for ProfileTM attenuation
correction. All of these systems have list-mode capabilities as required
for the proposed work herein. All systems are networked to a common
environment for processing and storage. The following research
computers are available for this work: 2 SUN Ultra SPARC 60 UNIX
based systems, 1 stand alone SUN SPARC 20, 5 Windows based PC’s
for word processing and data analysis. Printing, data analysis software,
C and C++ programming capabilities are also available. CVIT
implements source document control to all programming code for
collaborative development, version control and compliant commercial
software development under the FDA’s Good Manufacturing Practices
(GMP). The PET/CT laboratory where the proposed research will be
conducted has one NavigatorTM Workstation and one WizardTM
workstation. The imaging program also includes cardiac SPECT
services operating over a wide-area network integrating nine
laboratories and ten gamma cameras to a central laboratory for data
processing, clinical interpretation and reporting, and databasing of
approximately 150,000 patients with over 600 variables per patient.
Both facilities are located adjacent to the Saint Luke’s Hospital and the
Mid America Heart Institute (MAHI). The MAHI houses over 30 basic
research personnel and physician cardiac researchers and is the main
teaching hospital for the University of Missouri School of Medicine.
Through this arrangement, CVIT personnel have access to biostatistical
and databasing resources and personnel to perform cardiac related
research. CVIT also participates in the clinical scholars program
supporting M.D.s and research fellows from the Mid America Heart
Institute and graduate student collaboration with the University of
Missouri-Columbia’s Nuclear Engineering Department.
CVIT is recognized as one of the world leaders in Cardiac Imaging
Research. We work with investigator initiated research at the
government societal and industrial levels. We have partnerships with
major drug and device providers for simultaneous technology
development and are a leading patient recruiter for major drug and
device trials including:
Siemens Definition
Siemens Biograph
Siemens Accel
Siemens Gamma Prompts Scatter Correction
Philips CardioMD(AC)
Philips AstonishAC
Philips VantagePRO
GE Tl-201 database
Tyco IVIEW workstation
Syntermed (Normal Rb-82 databases)
Hitachi: whole-body imaging
GE: MIBG
Molecular Insight: BMIPP
Bracco: Teboroxime
CVT: Regadenosine
GE-Amersham: AC Tetrofosmin
BMS: Sestamibi
Bracco: Cardiogen
Bracco: Isoview
Tyco Mallinckrodt: Tl-201
Spectrum Dynamics
Lantheus Medical Imaging
CVIT is based in Kansas City, Missouri, and occupies independently-
leased facilities adjacent to Saint Luke's Cardiovascular Consultants.
All scientific and office computing facilities are networked through a
local area network internally and connected to all the imaging modality
computers and databases facilities at Saint Luke's Cardiovascular
Consultants. CVIT employs three internationally recognized full-time
PhD physicist/scientists in medical imaging, an internationally
recognized M.D. medical director, and a support staff of clinical research
associates, software programmers, technologists, administrative, grant
and technical writing staff. All employees are located at this facility with
full access to all Saint Luke's Cardiovascular Consultants equipment
and clinical operations per a research and technical service contract
with Saint Luke's.
The nuclear cardiology department operates its imaging services over a
wide-area network integrating 11 laboratories in office and hospital
environments with 11 SPECT cameras networked to a central laboratory
for data processing, clinical interpretation, reporting, databasing of
image, clinical and demographic data. A nuclear cardiology database,
established in 1987 contains over 120,000 patient entries with over 700
variables recorded per patient. This database is integrated with similar
databases for coronary catheterization, echocardiography and clinical
outcomes as a resource for clinical investigation. The center for
Cardiovascular and Radiological Imaging established in 2001 within
Saint Luke's Cardiovascular Consultants is a 2,200 sq. foot facility with
PET, PET/CT and CT laboratories for cardiac application.
The main facility for nuclear cardiology has 3 SPECT systems: 2 ADAC
dual 90 detector CardioTM systems, both with scanning Gd-153 line
sources for attenuation correction and a dual 90o detector Siemens e.
camTM with a fixed array of Gd-153 sources for ProfileTM attenuation
correction. All of these systems have list-mode capabilities as required
for the proposed work herein. All systems are networked to a common
environment for processing and storage. The following research
computers are available for this work: 2 SUN Ultra SPARC 60 UNIX
based systems, 1 stand alone SUN SPARC 20, 5 Windows based PC’s
for word processing and data analysis. Printing, data analysis software,
C and C++ programming capabilities are also available. CVIT
implements source document control to all programming code for
collaborative development, version control and compliant commercial
software development under the FDA’s Good Manufacturing Practices
(GMP). The PET/CT laboratory where the proposed research will be
conducted has one NavigatorTM Workstation and one WizardTM
workstation. The imaging program also includes cardiac SPECT
services operating over a wide-area network integrating nine
laboratories and ten gamma cameras to a central laboratory for data
processing, clinical interpretation and reporting, and databasing of
approximately 150,000 patients with over 600 variables per patient.
Both facilities are located adjacent to the Saint Luke’s Hospital and the
Mid America Heart Institute (MAHI). The MAHI houses over 30 basic
research personnel and physician cardiac researchers and is the main
teaching hospital for the University of Missouri School of Medicine.
Through this arrangement, CVIT personnel have access to biostatistical
and databasing resources and personnel to perform cardiac related
research. CVIT also participates in the clinical scholars program
supporting M.D.s and research fellows from the Mid America Heart
Institute and graduate student collaboration with the University of
Missouri-Columbia’s Nuclear Engineering Department.
CVIT is recognized as one of the world leaders in Cardiac Imaging
Research. We work with investigator initiated research at the
government societal and industrial levels. We have partnerships with
major drug and device providers for simultaneous technology
development and are a leading patient recruiter for major drug and
device trials including:
Siemens Definition
Siemens Biograph
Siemens Accel
Siemens Gamma Prompts Scatter Correction
Philips CardioMD(AC)
Philips AstonishAC
Philips VantagePRO
GE Tl-201 database
Tyco IVIEW workstation
Syntermed (Normal Rb-82 databases)
Hitachi: whole-body imaging
GE: MIBG
Molecular Insight: BMIPP
Bracco: Teboroxime
CVT: Regadenosine
GE-Amersham: AC Tetrofosmin
BMS: Sestamibi
Bracco: Cardiogen
Bracco: Isoview
Tyco Mallinckrodt: Tl-201
Spectrum Dynamics
Lantheus Medical Imaging
Cardiovascular Imaging Technologies
 |  |  |  |  |
Kansas City, MO 64111
ph: 816-531-2842
fax: 816-531-0643
scourter@cvit.com
ph: 816-531-2842
fax: 816-531-0643
scourter@cvit.com
Copyright 2010 Cardiovascular Imaging Technologies. All rights reserved.
CVIT scientist, Dr. Bai Ling
Hsu receives the Young
Investigator Award at the 2009
American Society of Nuclear
Cardiology Annual Meeting
Hsu receives the Young
Investigator Award at the 2009
American Society of Nuclear
Cardiology Annual Meeting
